During his talk he asked the first-, second- or third-generation immigrants in the audience to rise. He still owns a 6% stake in the company, part of an estimated $5.5 billion net worth that includes about $1.5 billion in Moderna options. The shares were sold at an average price of $139.00, for a transaction totalling $1,390,000.00. Biography of Noubar Afeyan Noubar B. Afeyan, Ph.D. has served as a member of our board of directors since 2013. Below are key takeaways from a conversation this week around Moderna's early days, its startup DNA, immigrant leadership, and why the recent focus on a COVID-19 vaccine should not be called a pivot. I have written two books about Mahler, in 1987 and 2010. They begin by asking What if? and iterate toward the unexpected answers resulting in the creation of first-in-category bioplatform companies with significant impact. Noubar, like so many immigrants who survived the Armenian Genocide and their descendants triumphed [over tragedy] and the world is a far better place for the contributions of our honoree, Kalustian said. [5][6] Talking about his background, Afeyan said: "One of the only unfortunate advantages Armenians have had by having gone through a genocide and having spread around the world is that we do have an experience of escaping and of immigrating and of constantly restarting. How I Built This: Moderna and Flagship Pioneering: Noubar Afeyan, Noubar Afeyan on the What's Your Problem? That is 99 percent of the room standing, he said. Every one of our companies is born to aspire to what Moderna has done, he told Forbes during an interview at Flagships offices overlooking the Charles River. Together with his partners, he has launched philanthropic projects including the Aurora Humanitarian Initiative, FAST Foundation, and the UWC Dilijan School. Modernas fifth-largest individual shareholder, president Stephen Hoge, sold $65.5 million worth of Moderna stock since March 2020; Hoges 0.4% stake in Moderna is worth roughly $300 million, but he also owns about $545 million in options. The program also was a fundraiser for the maintenance of Bostons Armenian Heritage Park on the Greenway and it did not disappoint; the roughly 500 people gathered there raised $700,000. [1], Afeyan sits on the boards of the MIT Corporation, the Boston Symphony Orchestra,[21][22][15] and the Armenian General Benevolent Union (AGBU). Indigo Agriculture was founded in 2013 to use microbes to make seeds more productive. Hu Kun is the chairman of Shenzhen-listed Contec Medical Systems, which makes a range of medical equipment including pulse oximeters and pulmonary devices used to check lung conditions. Entering the U.S. as an international student has shown to be a good avenue for starting successful companies for immigrants and America. King Charles' youngest son Prince Harry and his wife Meghan Markle's rep gave the BBC a rare update on whether they will attend his coronation next month. With $17 billion and a model of "parallel entrepreneurship," he can fund a lot of wild. It was only days after Pfizer announced clinical trials showed the vaccine was 90% effective at preventing COVID-19. Some, such as Moderna CEO Stphane Bancel and BioNTech cofounder Uur ahin, have become household names thanks to the vaccines they helped develop. Our sales over recent weeks and months were pursuant to a 10b5-1 plan put in place last December and executed in two installments following the passage of 60 days from the original filing, a spokesperson for Flagship told Forbes. He starts with those what-if questions. The best of these subsidiaries will eventually take on outside investors before (hopefully) going public. He points to his immigrant background and mentality as the driving forces of his philanthropic, scientific, and business work. "We didn't have to do that," Afeyan said. Moiderna Chairman Noubar Afeyan also reiterated a pledge Moderna made a year ago not to enforce patent infringement on anyone else making a coronavirus vaccine during the pandemic. Pfizers CEO is Albert Bourla. Now, back to the back story how Jews changed the world during the remarkable one hundred years, 1847-1947, according to Lebrecht. [40], In November 2020, Afeyan confirmed that the Canadian government had been among the first countries to pre-order the Moderna vaccine; the country is guaranteed to get some portion of the first batch dispensed to the public. [1] Was it perhaps because of your book about the Jewish composer Gustav Mahler? ahin is the CEO and cofounder of BioNTech, which he started alongside his wife and chief medical officer zlem Treci. Donald Trump cannot take credit for the vaccines. Afeyan, 59, is one of five billionaires associated with it, with an estimated $2.9 billion fortune (Bancel is another, worth some $7.5 billion). Chen Xiao Ying is an investor in e-commerce giant Alibabas online healthcare arm Alibaba Health Information Technology, which signed a deal with Chinese vaccine maker Sinovac in September to develop a digital platform for Sinovacs Covid-19 vaccine rollout. He received the Golden Door Award in 2017 from the International Institute of New England in recognition of his contribution to the US as a foreign-born American. Cambridge, MA. His company, Flagship Pioneering, is in the business of starting other companies using a methodological set of steps. Even after its recent pullback, Moderna stock is up eight-fold since March 2020. Have you faced such criticism? Moderna - founders Noubar Afeyan and Robert Langer and investor Timothy Springer - made it on Forbes' list of the 400 richest Americans after the company saw a COVID-fueled windfall. Gregorian is the former president of Brown University as well as the NewYork Public Library. Jewish mothers push their children to aspire to greatness and to genius, he explains. Noubar Afeyan is founder, Senior Managing Partner and CEO of Flagship Pioneering, a leading innovation and early-stage venture capital firm. In 2022, Afeyan was awarded an honorary Doctor of Science, honoris causa (D.Sc.) Afeyan, who became a U.S. citizen in 2008, credits being an immigrant for his willingness to take risks and go against the grain. If you're an immigrant, then you're used to being out of your comfort zone. His grandfather escaped to Bulgaria, where his father was born. Forbes 35th Annual Worlds Billionaires List: Facts And Figures 2021, Operation Wealth Speed: What A Record Number Of New, Self-Made Billionaires Says About Capitalism, These 11 Colleges Have Produced The Most Billionaire Alumni, The Covid Billionaire Who Wants To Put Undocumented Immigrants In Americas Finest Colleges, Kim Kardashian West Is Officially A Billionaire, The Worlds Richest Healthcare Billionaires In 2021, Meet The New Billionaire Behind Kazakhstans Surprisingly Hot Brokerage, The Top Richest Women In The World In 2021. Noubar Afeyan, founder of Flagship, said: "The expanded capital base is going to allow us to . He thanked the organizers on behalf of Mayor Martin J. Walsh, adding, We thank you for bringing the park to us and keeping it. He is best known for co-founding the biotechnology company Moderna, through his venture capital firm, Flagship Pioneering, and for co-founding humanitarian projects such as Aurora Prize and The Future Armenian. [33] and Future Armenian public initiative. The gala, like so many other events of the past year, was held "virtually" that is, it was livestreamed as a Zoom meeting to a group of viewers who signed up beforehand. Dr. Avak Kahvejian (Leo Gozbekian photo), In her opening comments, Barbara Tellalian, a tireless fundraiser for the park and the wife of its designer, architect Donald Tellalian, said the park as well as the evening was dedicated to what connects us, celebrating the American immigrant experience., Next, Armenian Heritage Foundation President James Kalustian brought a congratulatory message from Gov. The seeming courage it would take to do these things is rooted in being unrooted, he says. I cant resist giving a plug to the Jewish mother theory of genius, by the legendary Israeli entrepreneur and angel investor Yossi Vardi. [1] He has patented over 100 inventions. Miller is the founder and executive chairman of healthcare services provider Universal Health Services, which conducts testing for Covid-19 and treats patients at its network of hospitals across the U.S. Cao Xiaochun is the cofounder and director of pharmaceutical contract research outfit Hangzhou Tigermed Consulting, which supported clinical trials for CanSinos Covid-19 vaccine. Afeyan is Armenian, emigrated from Lebanon to Canada and eventually did his doctorate at MIT. Previously, he was a member of the founding team, director, and investor in highly successful ventures including Chemgenics Pharmaceuticals (acquired by Millenium Pharmaceuticals), Color Kinetics (acquired by Philips), Adnexus Therapeutics (acquired by Bristol-Myers Squibb), and Affinnova (acquired by AC Nielsen). Noubar Afeyan fully understood those risks when he co-founded Moderna in 2010. . Parks Newest Benefactors Megan (third from left) and Ron (2nd from right) Hovsepian with their family with Noubar Afeyan. Moderna, which is leading Americas response to the novel coronavirus, is a story of welcoming talent from all over the world. When he used to come home from school, she did not ask him what he learned that day, but rather asked, what good questions did you ask in school today, Isadore?Later, Rabis good questions helped led him to discover nuclear magnetic resonance the foundation of todays lifesaving MRI imaging devices. Is that, in fact, the story of the two Jewish vaccines? [7][1][3] He was the first PhD graduate from MITs Center for Bioprocess Engineering, at the time the only institution with that degree program. November 10, 2021. But thats the way Noubar thinks, and he has stuck with it the whole time.. Li Wenmei is the cofounder and general manager of diagnostic test supplier Guangzhou Wondfo Biotech, which makes a range of Covid-19 tests. (Each year the two halves of the sculpture are pried apart and reconfigured in a new way, to symbolize leaving the past and creating a new life. I think of it as chess. Benefactors of the Park from the outset, Dr. Afeyan and his wife Anna have endowed the Park's Fund for Programs. Afeyan, who Forbes estimates has a net worth of $2.3 billion, owns a large stake in Moderna largely through his majority ownership of Flagship, which he established in 2000 as a firm to build and fund promising startups in life sciences and technology. transformed Judaism from a cult based on ritual sacrifices to a religion whose main norm required every Jewish man to read and study the Torah in Hebrew and to send his sons to school or synagogue to learn to do so. The immigrant theme goes to the heart of the park, which has become a gathering place not only for Armenian commemorations, but also the site of the annual welcome reception for new US citizens who are sworn in at nearby Faneuil Hall, as well as other creative programs. Celebrating! And its not just the vaccine discoverers: companies that mass produce the vaccines and contract research firms that help firms run clinical trials have both reaped the rewards, creating new fortunes for people like Juan Lpez-Belmonte Lpez of Spanish pharma outfit Rovi and Karin Sartorius-Herbst and Ulrike Baro of German biopharma firm Sartorius AG. Afeyan had partnered with Vardanyan to establish Initiatives for Development of Armenia (IDeA),[23] which according to the Armenian government, has between 2007 and 2017 implemented different projects with a total cost of $550 million. Following the completion of the sale, the director now directly owns 2,187,209 shares of the company's stock, valued at $304,022,051. March 5th, 2021, 1:03 PM PST. While scientists had talked about the microbiome for years, when Afeyan first broached the idea in 2008 of exploring its role in disease, including autoimmune diseases and cancer, it was pretty far out on the fringe. In his remarks, honoree Afeyan singled out for praise his Swedish-born wife, Anna, his partner in his philanthropic endeavors, and expressed his hopes for his four children. The work in the microbiome, in part, led to more recent work on viruses as Afeyan and his team questioned whether there are viruses in our bodies that arent pathological. BOSTON Immigrants and their unique and vital contributions to the success of the US economy since the nations founding were the dominant themes of a program paying tribute to Dr. Noubar Afeyan, biotech innovator and philanthropist, on Wednesday, September 18, at the InterContinental Hotel. Draw a circle around what currently exists, Afeyan says, and then draw a bigger circle around whats adjacent to that. Podcast, What Evolution Can Teach Us About Innovation, The Billionaire Chairman Of Vaccine Maker Moderna Wants To Reinvent Scientific Entrepreneurship. Afeyan noted that he was especially delighted to have Gregorian there. Here's How His Formula Challenges Silicon Valley Dogma, In His Spare Time, Immigrant Noubar Afeyan Has Started 38 Companies In America, Do Not Sell or Share My Personal Information, Limit the Use of My Sensitive Personal Information. Lal is the executive chairman of Indian diagnostics chain Dr. Lal PathLabs, which offers Covid-19 tests at its clinics and collection points throughout India. [15] In 2020 Armenian Prime Minister Nikol Pashinyan lauded Afeyan, Vardanyan and Gregorian for "glorifying humanity," and "materializ[ing] the noble idea of immortalizing the memory of the innocent victims of the Armenian Genocide."[31]. His wife, Brenda, who studied at Harvard's Divinity School, recently launched a second foundation called Champions of Love. Godha chairs Mumbai-based generic drug manufacturer Ipca Labs, which had an FDA import ban softened in March 2020 to allow it to export the antimalarial drug hydroxychloroquine to the U.S. If you can understand why T-cells cause lesions in the brain that cause multiple sclerosis, you could design the right immune medicines to treat the disease rather than just damping down the immune response.. Deval Patrick and an official delegation from Armenia. Noubar Afeyan, chairman and co-founder of Moderna, joins Fareed to talk about the new Omicron coronavirus variant. Why Are Moderna Insiders Selling So Many Shares? What if, he asked his researchers, microorganisms living in our gutsthe microbiomecould help cure cancer? Wheres the value? How does one describe someone who has helped found 38 companies? Later reports raised its effectiveness to 95%. [41], Interview with Fareed Zakaria Dec. 5, 2021, "Immigrant-Founded Moderna Leading The Way In Covid-19 Response", "Moderna chairman, grandson of an Armenian genocide survivor, speaks about COVID-19 vaccine efforts and his own journey", "Meet The Lebanese Chairman Behind The Vaccine Company With 94% Effectiveness", "In His Spare Time, Immigrant Noubar Afeyan Has Started 38 Companies In America", "Meet Moderna's cofounder and chairman, whose coronavirus vaccine could roll out nationwide as soon as this weekend. As per our form 4 filing, this program covered 10 million shares, and is now concluded. On November 2nd, the Emmanuel Business Collaborative Speaker Series hosted Dr. Noubar Afeyan, the co-founder and chairman of Moderna and founder and CEO of Flagship Pioneering, a life science innovation firm that was conceived to offer an . The only criticism I have faced on this score has been from some Israeli interviewers who wanted to know why I regard Jews who converted as remaining part of the Jewish cultural unconscious. At a time when the world is just waking up to all the ways in which the planet was woefully ill . Highly Skilled Immigrants Drive U.S. Noubar Afeyan, an Armenian immigrant born in Lebanon, is one of the most successful biotech entrepreneurs at work. Afeyan is Armenian, emigrated from Lebanon to Canada and eventually did his doctorate at MIT. Another Novavax executive, president of research and development Glenn Gregory, sold nearly $20 million (pretax) in shares since March 2020. I thought I didnt have much of a downside, he says. The immigration experience includes hope, optimism, fear, uncertainly, struggle, leaving, adaptation, courage and above all, the feeling of being uprooted and being rootless, he said. During the Armenian genocide of 1915-16, in which as many as 1.2 million Armenian Christians living in the Ottoman Empire were killed, Afeyans paternal grandfather and great uncle were taken away twice, he says. Two Flagship fundsFlagship Ventures Fund IV, L.P. and Flagship Ventures Fund IV-Rx, L.P.sold 53% of their Moderna holdings, about 10.3 million shares, for more than $1.4 billion (pretax) in three sets of sales in late February and late March this year. He is the founder and chairman of Hyderabad-based drugmaker MSN Group, which started producing a low-cost version of the Covid-19 antiviral favipiravir in August. That is a huge, huge advantage. Afeyan, whose family moved to Canada as political refugees during the 1975 civil war in Lebanon, came to the US to earn his PhD in biochemical engineering from Massachusetts Institute of Technology. While Modernas chairman may be behind the biggest sales, the pharmaceutical executive who personally sold the most shares is Moderna CEO Stphane Bancel. Executives at Moderna and other pharma companies that developed vaccines for Covid-19, including Pfizer and Novavax, sold a further $400 million in shares over the same time period, for a total of $1.9 billion. [4], Afeyan was born to Armenian parents in Beirut, Lebanon in 1962. ( 25, 1962 [1], , ), , Flagship Ventures [2] . Dr. Noubar Afeyan, 58, is co-founder and chairman of the biotech company Moderna. While Moderna is by far its largest, other publicly traded graduates include Denali Therapeutics (market cap $6.3 billion), which is working on treatments for neurodegenerative diseases; Quanterix (market cap $2.1 billion), which makes tools to measure proteins for disease detection and treatment; and Rubius (market cap $1.3 billion), which uses red blood cells as treatments for cancer and autoimmune diseases. Like the Pfizer-BioNTech version, Modernas COVID-19 vaccine, too, has proven highly effective in clinical trials. British author Norman Lebrecht faces the media holding his Whitbread Book of the Year Award entry, The Song of Names, in London in 2003. Gong Yingying is the founder and chairwoman of Chinese healthcare tech firm Yidu Tech, which used its AI and big data technology to help the hard-hit city of Wuhan conduct contact tracing and coordinate its emergency response. In this talk, we are honored to be speaking with Noubar Afeyan, CEO and founder of Flagship Pioneering, a life science bioplatforms firm focused improving the human condition by . Noubar Afeyan, co-founder of Moderna Inc. and CEO of Flagship Pioneering Inc., discusses the remaining challenges in the Covid-19 vaccination efforts and the progress in creating shots for children. After PerSeptives acquisition by Perkin Elmer/Applera Corporation in 1998, he became senior vice president and chief business officer of Applera, where he initiated and oversaw the creation of Celera Genomics. He was an outlier then, he says, as both a young founder and an immigrant, at a time when neither was an advantage. Noubar entered biotechnology during its emergence as an academic field and industry, completing his doctoral work in biochemical engineering at MIT in 1987. (Leo Gozbekian photo). 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